Risk of Hypoglycemia during Hemodialysis in Diabetic and Non Diabetic Patients of ESRD: An Observational Study

Background: Patients with end-stage renal disease (ESRD) regardless of diabetes status are at increased risk of hypoglycemia due to dysregulation of the physiological processes maintaining normal glucose metabolism with a resultant array of adverse clinical outcomes endangering the life of patients.

Objective: The aim of this study is to measure the occurrence of hypoglycemia in patients of ESRD on hemodialysis with or without having diabetes at specified intervals.

Methods: This cross-sectional study will encompass 142 patients with ESRD on dialysis any age group with known ESRD, with or without having diabetes receiving dialysis for >/=3 months. It was be done in dialysis wing, Department of Nephrology of MMCH. The study was occurred from February 2022 to July 2022. Sampling technique was purposive sampling.

Result: Most of the patients (40.8%) were from 46-60 years of age group. In case of gender, male was predominant that was 69.7%. Regarding to diabetes mellitus, majority (80.3%) patients were free from this disease. On the other hand, 62.7% of patients were patient of hypertension. 130 patients had taken dialysis twice per week whereas, only 12 patients had taken dialysis thrice in a week. Most of patients had cardiovascular disease (51.7%) whereas only10.3% patients were affected to diabetic foot. Moreover, most of the patients were found (45.5%) in level 2 hypoglycemia.

Conclusion: Patients were more prone to have level 2 of hyperglycemia in both diabetic and non-diabetic patient. However, the diabetic patient had more chance of co-morbidities along with complications.